Dogoteka LactoAdapt Puppy supplements for puppies and kittens, promotes physiological intestinal function and strengthens immune protection, 15 g

Additional feed in the form of a paste with a dosing syringe for puppies and kittens, intended for support during the weaning period. with colostrum and maca INDICATIONS: Suitable for supporting puppies and kittens in the sensitive weaning phase. Stimulates the physiological function of the intestines and strengthens the immune system. It promotes the balance of intestinal flora and helps to strengthen the immune defense of puppies and kittens, useful in all cases where babies need additional support for physiological growth from birth to the end of weaning. Also useful: - when taking antibiotics, - when changing nutrition (switching from breast milk to artificial milk or to solid food), - nutritional disorders, - feeding disorders, - underweight, - intoxications Colostrum, commonly called first milk, is a fluid produced by the mammary gland. In dogs, it is released two days immediately after birth. It is a food that contains high levels of antibodies, proteins and key nutrients that help puppies develop their immune system and get the nutrients they need to survive in the first days. For babies, the risk of mortality in the newborn stage can be high. Therefore, it is very important to get colostrum from the mother. In certain cases, when the mother cannot adequately provide it, in order to ensure the survival of the newborns, it is possible to intervene by giving them colostrum of various origins. CATTLE ANIMALS FOR DOGS AND CATS Ideally, the newborn will suckle at the mother's nipple for colostrum within the first few hours after birth. Bovine colostrum is the most commonly used substitute for dogs because it contains high concentrations of immunoglobulins and other important nutrients that can help support the health of puppies and frail animals. Benefits of Bovine Colostrum for Dogs and Cats: - increase in immune resistance; - promotion of growth and development of puppies and kittens; Colostrum is a source of antibodies, carbohydrates, vitamins, proteins, fats, and minerals. PREBIOTICS THE TRIO OF PREBIOTIC FIBERS: - FRUIT OLIGOSACCHARIDES (FOS) - INULIN - MANNANO OLIGOSACCHARIDES (MOS) from brewer's yeast FOS, MOS and INULIN are dietary fibres, i.e. i.e. indigestible carbohydrates, undoubtedly important in both human and animal nutrition. Chemically, FOS and inulin are fructans (carbohydrates made up of repeating fructose units) with a short chain (FOS) and a slightly longer chain (INULIN), and are particularly abundant in foods such as chicory and Jerusalem artichoke. MOS are always dietary fibers, but are composed of mannose repeats and are mainly derived from yeast walls. All three substances act as prebiotics, i.e. i.e. they can be beneficial to health by regulating the gut microbiota, i.e. i.e. a collection of millions of microorganisms characteristic of the intestinal tract of various mammals. These microorganisms have a positive and vital effect on the health of the host. ((Suchodolski, 2011)). Indeed, there are several studies that consistently emphasize the symbiosis between health maintenance and gut microbiota balance. How do prebiotic fibers positively affect the microbiota? Humans and other mammals, including dogs and cats, do not have all the enzymes in their intestines to break down plant fibers (eg, fructooligosaccharides and inulin) (Flint HJ, 2012), so these, when consumed and passed into the small intestine, are not digested, but are fermented by the bacteria of the colonic microbiota, thus benefiting certain groups of beneficial bacteria (eg, Lactobacillus and Bifidobacterium). for abundance; this effect positively affects many functions, e.g. intestinal motility, cell integrity and biochemical networks of microorganisms. (Scott KP, 2015). Several studies have shown that the integration of fructooligosaccharides into the diet of dogs improves the absorption of various mineral substances and increases the number of Bifidobacteria, one of the beneficial microorganisms that actually live in the intestines of both humans and dogs and play an important role in the modulation of the immune system and digestive functions as well (Carlo Pinna1, 2018). However, it seems that the mechanism of action of MOS prebiotics is different - various studies emphasize their ability to selectively bind to receptors on the intestinal wall, making them inaccessible to pathogenic bacteria, which promotes the growth of "good" bacteria. PROBIOTICS – LACTOBACILLUS HELVETICUS – LACTOBACILLUS PARACASEI What are probiotics? In the feed sector, these are so-called zootechnical additives that stabilize the intestinal flora, i.e. i.e. microorganisms that, when given to animals, have a positive effect on their intestinal flora; (Europeo, 2003) they can actually colonize the gut of the host animal, giving it a beneficial effect. The attachment of a probiotic microorganism to the host's intestinal mucosa is considered the most important stage for colonization and further interaction with the host's epithelium and its immune system. (Mohsen Hanifeh, 2021). In fact, both pathogenic and commensal microorganisms (Commensals are microorganisms that live on any body surface or near the mucous membrane without harming the health of humans/animals) secrete various adhesin molecules on their surface that allow them to attach to various surfaces of the host. For this reason, when selecting strains of microorganisms with a probiotic effect, they must have a high ability to attach to the intestine. Probiotics can improve mucosal health through several mechanisms, including the production of short-chain fatty acids (SCFA), antimicrobial agents, modulation of the immune response, competitive elimination of pathogenic bacteria by interfering with their adhesion to the intestinal mucosa, and improvement of epithelial barrier functions. YANG®: This is a blend of inactivated yeasts, specifically Saccharomyces cerevisiae (commonly known as brewer's yeast) and Cyberlindnera jadinii. Yeasts are unicellular eukaryotic organisms that belong to the fungi kingdom. Brewer's yeast (Saccharomyces cerevisiae) is particularly used in animal nutrition due to its nutritional value, as it is rich in valuable macronutrients such as protein, as well as micronutrients such as selenium and chromium, B vitamins and many other substances beneficial to health. This effect is primarily due to the abundance of nutrients. Cyberlindnera jadinii is also a widely used yeast for its nutritional value as it is also rich in protein and vitamins. PETMOD® NUCLEOTIDES FROM BREWER'S YEAST. Nucleotides are the repeating elements that make up nucleic acids (DNA and RNA). They consist of three components: a nitrogenous base (purine or pyrimidine), a 5-carbon sugar that forms a nucleoside with the nitrogenous base, and one or more phosphate groups. Some studies conducted with fish have shown that dietary nucleotides have a beneficial effect on the intestine, promoting its growth and development. (Toshimasa Tsujinaka MD, 1999) For this reason, there is a growing demand for adding nucleotides to pet food, with the ultimate goal of contributing to normal immune function and intestinal health in pets. (Natalia Russo1, Nucleotide inclusion in pet food: effect of heat treatment, 2019) PSYLLIUM SEED POWDER Psyllium (Plantago psyllium) is a plant of the plant family (Plantaginaceae). It is known for its soothing and emollient properties for the digestive system, especially at the intestinal level. Due to the mucus on the surface of the seeds, when in contact with water, they swell and increase, forming a gel that can increase the amount of stool mass, soften its contents. Psyllium is therefore beneficial for normal intestinal transit. Finally, Psyllium contains fiber that acts as a prebiotic to ensure good gut microflora. MACA (CUTTER PEPPER) POWDER. Maca (Lepidium meyeni) is a plant belonging to the Brassicaceae family. Also called Andean ginseng, its roots contain important nutrients necessary for the body. They are rich in essential amino acids (such as isoleucine, lysine, methionine, tryptophan, valine, threonine, phenylalanine; they make up about 10%), mineral salts (iron, manganese, zinc, calcium, phosphorus), vitamins, carbohydrates, fatty acids and fiber. Due to the components of the phytocomplex, Maca has a tonic-adaptogenic effect, i.e. i.e. can non-specifically support the body's resistance and defense against various physical and mental stress factors. These refreshing and energizing properties are related to its effect on glycogenesis (the production of glucose from energy stores) during physical activity. Rich in A, C and B group vitamins, calcium, iron and zinc, it also has a positive effect on the nervous system. Composition: Composition: refined vegetable oils (sunflower), inactivated yeast (Saccharomyces cerevisiae and Cyberlindnera jadinii), fructose, sweet carob flour, hydrolyzed animal proteins (poultry), Saccharomyces cerevisiae yeast products (mannanoligosaccharides (MOS)), bovine colostrum powder 4%, mono-, di- and triglycerides of fatty acids, banana flour, fructooligosaccharides, chicory inulin, psyllium (plantain) seed husk powder, maca (Peruvian pepper) tuber powder, nucleotides, inactivated bacteria and their parts (Lactobacillus helveticus, Lactobacillus paracasei, Bifidobacterium spp.), sodium chloride, yeast products (Saccharomyces cerevisiae). Additives: technological additives: colloidal silicon dioxide. 1 g of paste corresponding to 1 cm contains: Inactivated yeast (Saccharomyces cerevisiae, Cyberlindnera jadinii) 125 mg Saccharomyces cerevisiae yeast products [mannanoligosaccharides (MOS)] 75 mg Bovine colostrum powder 40 mg Fructooligosaccharides 25 mg Chicory inulin 25 mg Psyllium (plantain) seed husk powder, 10 mg Maca (Peruvian pepper) tuber powder 5 mg Nucleotides 5 mg Inactivated bacteria and their parts, 10 mg, including: Lactobacillus helveticus 4 mg, Lactobacillus paracasei 4 mg, Bifidobacterium spp. 2 mg Yeast products (Saccharomyces cerevisiae) 1 mg. Doses and method of use: Use a syringe with a graduated dispenser to administer 1 g of paste for every 5 kg of puppy or kitten weight directly into the mouth or mix into the daily feed ration. Storage conditions: Keep tightly closed in a cool and dry place. The expiration date applies to the correctly stored product in its undamaged packaging. Packaging: LactoAdapt PUPPY® supplementary feed in paste form for puppies and kittens, syringe with graduated dispenser 15 g.